ASCO肺癌研究热点课件.pptVIP

L Zhang, et al ASCO 2011. # 7511 L Zhang, et al ASCO 2011. # 7511 ITT population Gefitinib n 148 Placebo n 148 p HR 95% CI PFS Median month 4.8 2.6 0.0001 0.42 0.32, 0.54 6-month % 47.3 15.0 12-month % 33.2 2.9 No. events, n % 124 83.8 144 97.3 OS Median month 18.7 16.9 0.2109 0.83 0.61, 1.12 6-month % 82.2 84.9 12-month % 68.8 66.0 No. events, n % 79 53.4 93 62.5 ORR % 23.6 0.7 0.0001 57.0 7.53, 431 DCR % 71.6 50.7 0.0001 2.66 1.61, 4.40 L Zhang, et al ASCO 2011. # 7511 Gefitinib Placebo HR 95% CI EGFR mut+ n 15 15 0.17 0.07, 0.42 Median PFS m