生物化学课后习1-3.docVIP

生物化学（上册）课后习题 第一章 糖类 1、环状己醛糖有多少个可能的旋光异构体？为什么？ 25=32因为环状己醛糖含有5个不对称碳原子。单糖由直链变成环状结构后，羰基碳原子成为新的手性中心，导致C1差向异构化，产生两个非对映异构体。羰基碳上形成的差向异构体称异头物。 2、含D-吡喃半乳糖和D-吡喃葡萄糖的双糖可能含有多少个异构体（不包括异头物）？含同样残基的糖蛋白上的二糖将有多少个异构体？ 每个单糖单位都能作为羰基供体，与另一个单糖单位的5个羟基形成糖苷键（C1,C2，C3，C4，C6），于是α-D-吡喃半乳糖-D-吡喃葡萄糖苷、β-D-吡喃半乳糖-D-吡喃葡萄糖苷、α-D-吡喃葡萄糖-D-吡喃半乳糖苷和β-D-吡喃葡萄糖-D-吡喃半乳糖苷各有五种，共5*4=20种。 糖蛋白上的二糖链其中一个单糖的C1用于连接多肽，C2，C3，C4，C6用于和另一单糖的C1形成糖苷键，算法同上，共有4*4=16个，考虑到二糖与多肽相连时的异头构象，异构体数目为16*2=32个。 5、D-葡萄糖的α、β异头物的比旋（【α】20D）分别为+112.2o和+18.7o.当α-D-吡喃葡萄糖晶体溶于水时，比旋将由+112.2o降至平衡值+52.7o.计算平衡混合液中α和β异头物的比率。假设开链形式和呋喃形式可忽略。 忽略开链形式和呋喃形式。设：α-D-吡喃葡萄糖所占比例x%，则β-D-吡喃葡萄糖所占比例为(100-x））Leu+→Leu0 + H+，Leu+? Leu0，【Leu+】Leu+】Leu+】Leu0→Leu-+H+， 因为Leu-? Leu0，所以【Leu-】Leu-→Leu0+OH-，【Leu0】】Leu-】】Leu0】】】））/+1的咪唑基释放出H+ 则中和咪唑基上H+的KOH=0.2*/+1=0.152mol 即需要[KOH]=0.152*2+0.048=0.352 mol/L。 取组氨酸盐酸盐41.92g（0.2mol），加入1mol/L KOH 352ml，水稀释至1L。 11、L-亮氨酸溶液（3.0g/50ml，6molHCI）在20cm旋光管中测得旋光度+1.81o，计算L-亮氨酸在6molHCI中的比旋。 比旋光度[α]D25=（旋光度*100）/（光径长度dm*浓度g/100ml） L-亮氨酸在6molHCI中的比旋=（+1.81*100）/（2*6.0）=+15.1o lujianhua (South area ahead Office Director and to war victory)]. County Government operates 3 Civil Affairs, finance, education and Finance Committee, with espionage, sabotage, standing and political team. Soon, the tomb of the Wujiang District Committee of the Kuomintang relocated to the countryside village. Pre-war, strict tomb for seventh district, its regional range for this Taoyuan town and town of Nan Ma Street, and Tan Qiu street of rotten Brook Tang West of area, in Wujiang South border, and Zhejiang Province Tongxiang County, and Wuxing County adjacent, ancient for two province (River, and Zhejiang) three House (Suzhou, and huzhou, and jiaxing) seven County (wuxing, and return Ann, and Tongxiang, and jiaxing, and show water, and Wujiang, and earthquake Ze) of make, is located in remote, territory size Lake swing dotted, river port criss-cross, easy hidden combat, and no Highway, traffic inconvenience. Therefore, this has become the refuge of many,