MBg-2Geneconcept重点.pptVIP

Gene locus DNA 双螺旋结构模型 (DNA Double Helix Model) 1938. W. T. Astbury 1950. Erwin Chargaff A + G / T + C = 1 A+T = G + C 1952.??? Alexander Todd? Nt~~Nt ~~Nt~~Nt~~Nt X~ ray photograph of DNA ? Rich AT form rich GC form 3’, 5’ phosphodiester bond 1953. Watson Crick Right handed B-form DNA Double helix Model 碱基的重叠与堆积 G-C pair, held together by three hydrogen bonds A-T pair , held together by two hydrogen bonds 1 6 2 3 4 2 The hydrogen-bonded base pairs of DNA. The figure shows the position and length of the hydro