胃食管反流病24小时食管pH监测.docVIP

胃食管反流病24小时食管pH监测分析作者：杨军????作者单位： 濮阳市油田总医院消化科，河南 濮阳 457001 【摘要】? 　　目的 探讨24小时食管pH的监测对胃食管反流的诊断价值及内镜阴性患者是否存在反流。方法 对95例有胃食管反流症状者进行24小时pH监测，根据检测结果，分析得出Johnson DeMeester计分。用pH＜4.0的总时间百分比、Johnson DeMeester计分进行分析。结果 食管黏膜酸暴露pH＜4.0的总时间百分比越长、Johnson DeMeester计分越高，临床症状及食管炎程度就越重；Johnson DeMeester计分内镜阳性（食管炎）组明显高于内镜阴性组 P＜0.05）内镜阴性组食管黏膜酸暴露异常仅为36.59％（15/41）。结论 食管炎患者有明显的胃食管反流，且反流症状的发生、程度、镜下食管炎表现与食管酸反流密切相关，部分内镜阴性患者反流症状的发生不伴有酸反流。 【关键词】? 胃食管反流病；24小时食管pH监测；食管炎 　　Analysis on 24hour pH Monitoring of Esophagus in Gastroesophageal Reflux Disease 　　Yang Jun, the General Hospital of the Oilfield in Puyang City, Henan Province 457001 　　ＡＢＳＴＲＡＣＴ? Ｏｂｊｅｃｔｉｖｅ? To discuss the diagnostic value of 24hour pH monitoring of esophagus for gastroesophageal reflux disease and to judge reflux in the patients with negative endoscopic examination.Ｍｅｔｈｏｄｓ? 95 cases with symptoms of gastroesophageal disease received 24hour pH monitoring of esophagus, Johnson Demeester score was gained by analyzing the results; the total time of acid exposure pH 4.0 and Johnson Demeester score were analyzed.Ｒｅｓｕｌｔｓ? The longer the total time of esophageal mucosal acid exposure pH 4.0 was, the higher Johnson DeMeester score was, and the more severe the clincal symptoms and esophagitis were; the Johnson DeMeester score of patients with positve endoscopic examination esophagitis was obviously higher than that of patients with negative endoscopic examination P 0.05 , the abnormity of acid exposure in patients with negative endoscopic examination was only 36.59 15/41 .Ｃｏｎｃｌｕｓｉｏｎ? Patients with esohagitis have obvious gastroesophageal reflux, the occurrence of the symptoms, its degree and the manifestation of esophagitis under the scope are closely correlated to esophageal acid reflux; some patients with negative endoscopic examination have the occurrence of reflux symptom without acid reflux. 　　ＫＥＹＷＯＲＤＳ? gastroesophageal reflux disease??? 24hour pH monitoring of esophagus??? esophagitis 　　胃食管反流病（GERD）是指胃、十二指肠内容物反流入食管引起烧心、