第38届ICH理论试题及答案.doc

General Directions Write your name and code number on each page of the answer sheet. You have 5 hours to finish the task. Failure to stop after the STOP command may result in zero points for the task. Write answers and calculations within the designated box. Use only the pen and the calculator provided. There are 23 pages of Problems and 19 pages of Answer Sheet. An English-language version is available. You may go to the restroom with permission. After finishing the examination, place all sheets including Problems and Answer Sheet in the envelope and seal. Remain seated until instructed to leave the room. Constants and useful formulas Gas constant R = 8.314 J K-1 mol-1 Faraday constant F = 96485 C mol-1 Use as standard pressure: p = 1.013?105 Pa Use as standard temperature: T = 25°C = 298.15 K Avogadro’s number NA = 6.022?1023 mol-1 Planck constant h = 6.626?10-34 J s Speed of light c = 3.00?108 m s-1 (G = (H - T(S (G = - nFE (G0 = - RT?lnK (G = (G0 + RT?lnQ with Q = (H(T1) = (H0 + (T1 - 298.15 K)?Cp (Cp = constant) Arrhenius equation k = A ? Ideal gas law pV = nRT Nernst equation E = E0 + Beer- Lambert Law A = log= (?c?d V(cylinder) = (r2h A(sphere) = 4(r 2 V(sphere) = (r 3 1 J = 1 N m 1 N = 1 kg m s-2 1 Pa = 1 N m-2 1 W = 1 A V = 1 J s-1 1 C = 1 A s 1. Avogadros number (5 pts) Spherical water droplets are dispersed in argon gas. At 27oC, each droplet is 1.0 micrometer in diameter and undergoes collisions with argon. Assume that inter-droplet collisions do not occur. The root-mean-square speed of these droplets was determined to be 0.50 cm/s at 27oC. The density of a water droplet is 1.0 g/cm3. 1-1. Calculate the average kinetic energy (mv2/2) of this droplet at 27oC. The volume of a sphere is given by (4/3) π r3 where r is the radius. If the temperature is changed, then droplet size and speed of the droplet will al