Effect of metoprolol on myocardial apoptosis after coronary microembolization in rats.docVIP

Effect of metoprolol on myocardial apoptosis after coronary microembolization in rats 　　BACKGROUND： Coronary microembolization （CME） is a serious complication following percutaneous coronary intervention （PCI） in patients with acute coronary syndromes. The use of metoprolol before PCI can significantly protect ischemic myocardium from myocardial damage， but the function of metoprolol in the treatment of CME is not entirely clear. This study was to explore the effect and significance of metoprolol on myocardial apoptosis and caspase-3 activation after CME in rats. 　　METHODS： Thirty rats were r