CKD-MBD与新型磷结合剂资料.ppt

* Cognitive deterioration occurs over time in ESRD patients. This slide addresses the issue of whether there is clinical evidence for adverse effects of lanthanum carbonate treatment. The data shown here were obtained from a sub-analysis of a 2-year trial comparing lanthanum carbonate with standard therapy (SPD405-307). Cognitive function was assessed using computer-controlled tasks from the Cognitive Drug Research cognitive assessment system. Patients were assessed on three attentional tasks (simple reaction time, digit vigilance and choice reaction time), one working memory task (numeric wor