妥方案被证实-卒中汇编.ppt

EMA（欧盟药品管理局）：瑞舒伐他汀40mg禁用于亚裔人群 2013 Crestor PI revised August 2014 CRESTOR SmPC May 2013 available at .uk/emc/document.aspx?documentid=11976# 2013 瑞舒伐他汀英文说明书 1 2013 Electronic Medicine Compendium (UK) 英国电子药品摘要2 ThemeGallery is a Design Digital Content Contents mall developed by Guild Design Inc. 8.8 亚裔患者 ….药理学研究证实，瑞舒伐他汀在亚裔人群的血药浓度是高加索人群的2倍，用于亚裔人群需要调整剂量…. 2.4 亚裔患者使用剂量 …. 由于在亚裔人群中瑞舒伐他汀血药浓度增加，因此瑞舒伐他汀在亚裔人群的起始剂量为5mg…. Race Increased systemic exposure has been seen in Asian subjects. The recommended start dose is 5 mg for patients of Asian ancestry. The 40 mg dose is contraindicated in these pati