chapter 15 Reactions of Alcohols.pptVIP

Tosylate Esters Alcohol + p-Toluenesulfonic acid, TsOH Acid chloride is actually used, TsCl Sulfate Esters Alcohol + Sulfuric Acid Nitrate Esters Phosphate Esters Phosphate Esters in DNA Alkoxide Ions ROH + Na (or NaH) yields sodium alkoxide RO- + 1° alkyl halide yields ether (Williamson ether synthesis) End of Chapter 11 Chapter 15Reactions of Alcohols Organic Chemistry, 6th EditionL. G. Wade, Jr. Yunfeng Chen School of Chemical Engineering Pharmacy chyfch@ Types of Alcohol Reactions Dehydration to alkene Oxidation to aldehyde, ketone Substitution to form alkyl halide Reduction to alkane