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荷瘤小鼠的应激相关性抑郁状态研究 池洁 （上海交通大学医学院临床医学八年制 上海） 摘 要：目的 探讨荷瘤小鼠的应激行为变化以及荷瘤对小鼠脑源性神经营养因子结果The Stress-related depression in H22 tumor-bearing mouse Chi Jie （Department of Clinical Medicine of 8 years program, School of Medicine, Shanghai Jiaotong University, Shanghai 200025） Abstract: Objective To study stress behavior and the expression of brain derived neurotrophic factor （BDNF） in H22 tumor-bearing mice. Methods The behavior changes and the expression of BDNF in the cerebrum and hippocampus were studied in H22 tumor-bearing mice. Results In the tail suspension test, the immobile time of the