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Combinatorial Chemistry Online: Volume 13, Issue 10, October 2011N.K. Terrett, Ensemble Therapeutics Corp., Cambridge, MA 02139, USAAvailable online 1 October 2011.Article Outline1. Current literature highlights1.1. A sparse matrix library design strategy2. A summary of the papers in this month’s issue2.1. Solid-phase synthesis2.2. Solution-phase synthesis2.3. Scaffolds and synthons for combinatorial libraries2.4. Solid-phase supported reagents2.5. Novel resins, linkers and techniques2.6. Library applicationsReferencesFurther reading1. Current literature highlights1.1. A sparse matrix library