培训课件_群体药代动力学及其应用.pptVIP

* Based on the population PK analysis, the dose individualization was conduct with C-TDM, a computer software for therapeutic drug monitoring. 1 or 2 CsA observations, the dose patient demographic information, the typical value of PK parameter were involved in the population model, to estimates the inter-indv variations, and to conduct population, subpopulation and individual predictions and their C.I. Then, based on the therapeutic window, the typical PK parameters, and the estimated individual variability, the desired, individualized dosing amount was calculated. * 利用数据库来管理信息首先就是要设计一个结构，合