CD4+調节性T细胞及其在类风湿关节炎中的研究进展.docVIP

【摘要】? 调节性T细胞（Treg）是一群具有免疫调节功能的T细胞亚群，其功能异常可导致多种自身免疫病。类风湿关节炎（RA）是一种主要累及周围关节的多系统炎症性自身免疫病，多种免疫细胞与其发病存在密切关联。本文回顾近年来有关CD4+Treg及其在RA中的研究进展情况，为进一步研究RA的发病机制和治疗打下基础。 【关键词】? 调节性T细胞；类风湿关节炎 Progress in Studies of CD4+ Regulatory T Cells and Their Role in Rheumatoid Arthritis ??? HUANG Zhixiang? ZHENG Benrong? LI Tianwang ??? (Department of Rheumatology, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China) ??? Abstract: Regulatory T cells (Tregs) are a subset of T cells which are involved in keeping peripheral immune tolerance and have attracted much interest in their role in