Blood cells across the sinusoid into blood stream To enter the blood stream, mature blood cells, except for platelets, must pass through the sinusoidal wall to get into the sinuses. They actually migrate through the cytoplasm of the lining endothelial cell. Two changes in maturing cells permit this: ? (i) they lose their adherence receptors and (ii) they become more deformable ASSESSMENT OF MARROW FUNCTION The best indication of normal marrow function is a normal full blood count, i.e. all blood cells are within normal limits. Abnormal marrow function can be evaluated in severa
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