西酞普兰与老抑郁的治疗WK修稿_培训课件.pptVIP

* 1. 卒中患者抑郁发病率高达40% (40) ，功能障碍更严重(41, 42) ，死亡率增加（3年HR1.13） (43). Depression is seen in up to 40% of patients suffering stroke (40) and is associated with worsened functional impairment (41, 42) and increased mortality (HR at 3 years: 1.13, 95% CI 1.06–1.21) (43) （出自：Taylor D. Antidepressant drugs and cardiovascular pathology: a clinical overview of e?ectiveness and safety. Acta Psychiatr Scand. 2008: 118: 434–442） 40. Robinson RG, Bolduc PL, Price TR. Two-year longitudinal study of poststroke mood disorders: diagnosis and outcome at one and two years. Stroke 1987;18:837–843. 2.抑郁症状的发生可早在脑病变后