titzetal.,theproteininteractomeoftreponemapallidum.docVIP

Titz et al., The protein interactome of Treponema pallidum. Extended Discussion and Materials Methods Results and Discussion An integrated view of DNA-metabolism related processes (Figure 4): Each large-scale interaction study covers a given functional complex only to a limited extend. This is due to the high false-negative rate of the employed method, which can be as high as 96% for Y2H (1) and which we have estimated to be in the range of 77% in our study. Integration of several datasets is the first choice to increase the coverage as has been recently demonstrated by our group (2). Here, w