Chapter12AlkeneReactionsPart2课程.pptVIP

Chapter 12 Alkene Reactions Part 2 Hydroboration—Oxidation Hydroboration Borane, BH3, is stable in ether or THF because they stabilize the Lewis acid by bonding as Lewis bases BH3 will add to alkenes: Mechanism: BH3 electrophile, p-bond nucleophile Boron binds to the less hindered Carbon (regioselective and syn addition) due primarily to steric factors Oxidation of Alkylborane gives an Alcohol Oxidation Mechanism Result of Hydroboration—Oxidation is Anti-Markovnikov H2O addition Example Oxidations of Alkenes Peroxycarboxylic Acids are useful oxidation reagents for alkenes Ge