2016肺功能不全中山大学课程.pptVIP

Respiratory Failure Functional shunt and  Anatomic shunt Anatomic shunt No blood –gas exchange Applying O2 can’t increase PaO2 Functional shunt blood –gas exchange decrease Applying O2 can increase PaO2 Pathogenesis of ARDS Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. Stimulus Complement activation Pulmonary edema Lysosomal proteinase Active oxygen Pulmonary vasoconstiction Arachidonic acid metabolites Epithelial and endothelial Cell damage C5a Sequestration of neutrophils i