王永强银屑胶囊联合窄谱中波紫外线治疗寻常型银屑病疗效观察.doc

银屑胶囊联合治疗[摘 要] 目的 观察银屑胶囊口服联合窄谱中波紫外线照射治疗寻常型银屑病的疗效。方法 将120例患者随机分为两组，治疗组60例给予银屑胶囊口服联合窄谱中波紫外线照射；对照组例，仅给予治疗周判效。治疗组有效率.67%，对照组为.33%，两者差异有(P＜0.05)[关键词] 银屑胶囊；； [中图分类号] R 758.63； [] B Curative Effect Observation of Yin-xie Capsule combined with Narrow band ultraviolet B in the Treatment of Psoriasis Vulgaris WANG Yong-qiang, ZHAO Jian-wei, ZHAO Gui-xiang, DING Qiu-yun, LIU Chun-mei (Department of Dermatology,Affiliated Hospital of Hebei University, Baoding 071000, China) [Corresponding author] WANG Yong-qiang, E-mail:wan6618@139.com [Abstract] Objective To observe the efficacy of Yin-xie Capsule combined with Narrow band ultraviolet B in the Treatment of Psoriasis Vulgaris. Methods 120 patients were randomly divided into two groups, 60 cases in treatment group were treated with Yin-xie Capsule oral, combined with Narrow band ultraviolet B; And 60 cases in control group were only received Narrow band ultraviolet B. All of the patients in the two groups were treated for 12 weeks to evaluate the curative effect. Results The effective rate of the treatment group was 81.67% and in the control group was 58.33%. There was a significant difference between the two groups (P＜0.05) Conclusion It is effective of Yin-xie Capsule combined with Narrow band ultraviolet B for Psoriasis Vulgaris, and it has low side effect. [Key words] Yin-xie Capsule; Narrow band ultraviolet B; Psoriasis Vulgaris 银屑病是一种常见的慢性复发性炎症性皮肤病，发病机理不完全清楚。寻常型银屑病是银屑病里最常见的临床类型，一般病程长，治疗效果不理想，给患者造成较大的痛苦。笔者于20年月至201年月采用例，取得疗效。 资料与方法 1.1 患者均来自科门诊，符合的诊断[1]，其中男例，女例，年龄～岁病程月至年无严重肝肾疾病 采用分段随机分组法，将120例患者2组，治疗组例治疗组病程病程(P＞0.05)，具有可比性。 1.3 治疗方法 治疗组给予（制药有限公司）（Waldmann公司生产，波长309~313nm，峰值311nm）/周；对照组仅给予窄谱中波紫外线照射，3次/周。。 1. 疗效判定标准 [2]，计算治疗前后PASI评分的变化百分率，即疗效指数。疗效指数=（治疗前PASI评分-治疗后PASI评分）/治疗前PASI评分×100%。治愈为疗效指数≥90%；显效为疗效指数60%～89%；好转为疗效指数20%～59%；无效为疗效指数＜20%。有效率以治愈加显效计算[3]。 1.5 统计学处理 对每组治疗前后的PASI评分及两组治疗后的PASI评分分别进行t 检验，对两组治疗有效率进行X2检验，P＜0.052 结果 2.1 结果 见表1。治疗组和对照组治疗的有效率分别为.67%和.33%，两者差异有 (X2=7.778，P＜0.05)。 表1 疗效比较（例）