依达拉奉治疗急性缺血性脑血管病的临床分析.docVIP

依达拉奉治疗急性缺血性脑血管病的临床分析 　　 　　 　　[摘要] 目的 探讨依达拉奉治疗急性缺血性脑血管病的临床效果。 方法 选取本院收治的急性缺血性脑血管病患者98例，随机分为实验组和对照组，对照组给予常规治疗，实验组在对照组基础上加用依达拉奉治疗，比较两组患者治疗前后神经功能缺损情况和日常生活能力指数以及治疗整体效果。 结果 治疗组治疗后的神经功能评分和日常生活能力指数评分均优于对照组，差异有统计学意义（P0.05），实验组治疗总有效率为96.0%，显著高于对照组的75.0%，两组差异有统计学意义（P0.05）。 结论 依达拉奉在治疗急性缺血性脑血管病中效果显著，值得临床推广应用。 　　[关键词] 依达拉奉；急性缺血性脑血管病；疗效 　　[中图分类号] R743[文献标识码] A[文章编号] 1674-4721（2014）05（a）-0046-03 　　 　　Clinical analysis of edaravone treatment of acute ischemic cerebrovascular disease 　　ZHANG Fan 　　Department of Internal Medicine,People′s Hospital of Jingang Town in Zhangjiagang City of Jiangsu Province,Zhangjiagang 215631,China 　　[Abstract] Objective To explore clinical curative effect of edaravone treatment of acute ischemic cerebrovascular disease. Methods 98 patients with acute ischemic cerebrovascular disease in our hospital were randomly divided into experimental group and control group,control group was given conventional treatment,the experimental group was given edaravone on the base of control group.The neurologic deficits and daily life ability index of the two groups of patients before and after treatment,and the overall effect were compared. Results The nerve function score and daily life ability index score of treatment group was better than that of control group after treatment,the difference was statistically significant (P0.05),the total effective rate of experimental group was 96.0%,which was significantly higher than that of control group of 75.0%,the differences between the two groups was statistically significant (P0.05). Conclusion Edaravone has an good effect in the treatment of acute ischemic cerebrovascular disease,which is worth clinical promoted. 　　[Key words] Edaravone;Acute ischemic cerebrovascular disease;Curative effect 　　随着现代社会的发展，人们生活水平日益提高，人口老龄化进程加速，急性缺血性脑血管病的老年患者逐年增加[1]，严重威胁患者的生命健康。由于患者脑部血供障碍导致缺血缺氧，局部脑组织发生缺血性坏死或软化，自由基引发脑缺血缺氧损害[2]，该病起病急，发展快，病情较重，致死致残的概率较高，因此临床上能否及时有效地采取安全有效的治疗方法显得尤为重要[3]。依达拉奉是一种新型的自由基清除剂，能清除体内的活性氧分子以及羟自由基，通过抑制脂质过氧化来减少细