贝复新联合莫匹罗星治疗尖锐湿疣CO2激光术后.docVIP

贝复新联合莫匹罗星治疗尖锐湿疣CO2激光术后 创面疗效观察 [摘要] 目的：观察贝复新（rb-bFGF）Curative effect of mupirocin ointment combined with Beifuxin Gel on patients with condyloma acuminatum after treatment of CO2 laser SUN Cui-qun, YANG Li-hua, YU Guang-zhao, YUAN Shao-kang.Yantai dermatological?control?station, 264000 [Abstract] Objective: To study the curative effect of mupirocin ointment combined with Beifuxin Gel on patients with condyloma acuminatum (CA) after treatment of CO2 laser. Methods: 76 patients with CA after treatment of CO2 laser were divided into two groups: the treatment group(n=44) treated with mupirocin ointment combined with Beifuxin Gel and the control group(n=32) treated with mupirocin. The wound healing situation were compared between the two groups. Results: The total effective in the treatment group was 95.5% and in the control group was 81.3%, which showed significant difference (P0.05). The average healing time in the treatment group and the control group was (6.17±1.21)d and (7.92±1.20)d respectively, which also showed statistical difference (P 0.01). Conclusion: Mupirocin ointment combined with Beifuxin Gel can accelerate wound healing effectively on patients with CA after treatment of CO2 laser, which is valuable for the clinical treatment. [Key words] Beifuxin Gel； Mupirocin ointment; Condyloma acuminatum; CO2 laser 尖锐湿疣是由人乳头瘤病毒(HPV)感染引起的生殖器、肛周等部位鳞状上皮疣状增生性病变的性传播疾病，在我国近年来发病率逐年增高。 临床上通常采用激光、电灼、冷冻、微波及应用腐蚀剂等方法去除疣体。激光疗法虽能在一定程度上消除疣体，但由于其疣体生长在外阴及肛周，环境潮湿，清洁度相对较差，因此术后常发生创面感染，导致愈合延迟，1 影响治疗效果。目前我所采用贝复新联合莫匹罗星外用治疗尖锐湿疣CO2激光术后创面，使创面愈合时间明显缩短，治愈率明显提高，疗效显著。 1 资料与方法 1.1 临床资料 选取201年2014年月例尖锐湿疣患者，排除合并HIV感染病例％～％调查结果采用17. 0录入，进行描述性分析和 χ2。P0.05)。详见表1。 2.1 临床治疗达到有效所需时间 治疗组平均为6.17天，低于对照组的7.92天，两者差异有统计学意义（t=5.83, P 0.01）。详见表2。 表1： 治疗组与对照组临床疗效比较[例(％)] 组别 例数 治愈 显效 好转 无效 治疗组 44 37(84.1) 5(11.4) 2(4.5) 0 对照组 32 20(62.5) 6(18.8) 6(18.8) 0 X2=3.97, P 0.05 表2： 治疗组与对照组临床治疗达到有效所需时间比较[例] 组别 例数 第四天 第五天 第六天 第七天 第八天 第九天 第十天 平均（天） 治疗组 42 3 8 18 7 4 2 0 6.17±1.21 对