基因和如何运行(英文版).pptVIP

Mutation Codon Change to DNA sense strand Change in Amino Acid S (sickle cell anaemia) 6 GAG to GTG Glu to Val C (cooley’s syndrome) 6 GAG to AAG Glu to Lys GSan Jose 7 GAG to GGG Glu to Gly E 26 GAG to AAG Glu to Lys MSaskatoon 63 CAT to TAT His to Tyr MMilwauki 67 GTG to GAG Val to Glu OArabia 121 GAA to GTA Glu to Val ? 2010 Paul Billiet ODWS Mutation in the hemoglobin gene Let’s Go to the Video! DNA mutation DNA mutation Question Q1) What is the type of genetic mutation in Sickle Cell Anaemia? Q2) How could a single base substitution result in a shortened protein product?