DIC的现代治疗-王春森.pptVIP

DIC的定义 Disseminateded Intravascular Coagulation (DIC)是由多种疾病引起的一种临床病理综合征 是不同病因损伤微血管体系导致凝血活化,全身微血管透明血栓形成、凝血因子大量消耗并继发纤溶亢进的临床综合征 其临床特征是器官功能衰竭，血小板减少，凝血因子消耗和减少、出血表现 DIC的病因 Malignancy Leukemia Metastatic disease Cardiovascular Post cardiac arrest Acute MI Prosthetic devices Hypothermia/Hyperthermia Pulmonary ARDS/RDS Pulmonary embolism Severe acidosis Severe anoxia Collagen vascular disease Anaphylaxis DIC的病因 Infectious/Septicemia Bacterial Gm - / Gm + Viral CMV Varicella Hepatitis Fungal Intravascular hemolysis Acute Liver Disease Tissue Injury trauma extensive surgery tissue necrosis head