理中汤加减配合雷火灸治疗溃疡性结肠炎（缓解期）脾肾阳虚证临床观察.docVIP

理中汤加减配合雷火灸治疗溃疡性结肠炎（缓解期）脾肾阳虚证临床观察 　　doi：10.3969/j.issn.1007-614x.2014.14.47 　　摘 要 目的：观察口服理中汤加减配合雷火灸治疗溃疡性结肠炎（缓解期）脾肾阳虚证的临床治疗效果。方法：66例溃疡性结肠炎脾肾阳虚证患者随机分为两组，治疗组32例，对照组34例。治疗组给予口服理中汤加减中药汤剂，同时应用雷火灸；对照组给予美沙拉嗪片口服，2.0g/日。两组均治疗12周。观察两组间临床综合疗效、中医证候疗效及症状、体征总积分的治疗前后变化。结果：治疗组在临床综合疗效、中医证候疗效及症状、体征总积分均优于对照组。结论：理中汤加减配合雷火灸治疗溃疡性结肠炎（缓解期）脾肾阳虚证疗效肯定。 　　关键词 理中汤加减 雷火灸 溃疡性结肠炎（缓解期） 脾肾阳虚证 疗效观察 　　Clinical observation of Lizhong decoction with thunderbolt moxibustion treatment on ulcerative colitis（remission）spleen deficiency syndrome 　　Ya Dong，Bai Chunying，Ma Yaoyao，Zang Dawei 　　Department of spleen and stomach diseases of the traditional Chinese Medicine Academy of Sciences of Jilin province，130021 　　Abstract Objective：To observe clinical effect of oral Lizhong decoction with thunderbolt moxibustion treatment on ulcerative colitis（remission）spleen deficiency syndrome.Methods：66 patients with ulcerative colitis spleen deficiency syndrome were randomly divided into two groups，32 patients in the treatment group，34 patients in the control group.The treatment group received oral Lizhong decoction decoction，while applying thunderbolt moxibustion.The control group oral mesalazine tablets，2.0g/day.Both groups were treated for 12 weeks.Comprehensive clinical efficacy were observed between TCM syndromes and symptoms，and signs total score changed afer treatment.Results：The treatment group in the comprehensive clinical efficacy，TCM syndromes and symptoms，signs total score were all better than the control group.Conclusion：Lizhong decoction with thunderbolt moxibustion treatment on ulcerative colitis（remission）spleen deficiency syndrome is effective. 　　Key words Lizhong decoction；Thunderbolt moxibustion；Ulcerative colitis（remission）；Spleen deficiency syndrome；Efficacy 　　溃疡性结肠炎（UC）属于炎性肠病，它是一种免疫性、慢性、复发性疾病。临床以腹泻、黏液脓血便、腹痛、里急后重为主要表现。随着现代科技手段的日新月异，研究者认为UC发病机制与遗传、免疫、细胞因子、肠黏膜屏障功能、自由基等有关，故现代医学治疗药物多以5-氨基水杨酸、糖皮质激素、免疫抑制剂、生物制剂等为主。由于病程长、复发率高、费用较贵、又有癌变的风险，被世界卫生组织称为现代难治病之一。笔者在临床工作中治疗UC缓解期脾肾阳虚证采用灸药并用，临床治疗效果好，现总结报告如