米非司酮和米索前列醇配伍羊膜腔内注射利凡诺终止中期妊娠的临床分析.docVIP

米非司酮和米索前列醇配伍羊膜腔内注射利凡诺终止中期妊娠的临床分析 　　doi：10.3969/j.issn.1007-614x.2014.16.33 　　摘 要 目的：研究探讨利凡诺联合米非司酮与米索前列醇对于终止妊娠的临床效果，并对其并发症的发生率进行探讨，为临床终止14～28周中期妊娠提供更多的理论参考依据。方法：对2008年1月-2013年1月收治的300例14～28周中期妊娠妇女的临床资料进行回顾性分析。结果：观察组终止妊娠总有效率97.33%，对照组80.67%，两组之间差异具有统计学意义（P0.05）。在妊娠物排出时间以及手术后并发症等方面，对照组与观察组之间比较差异有统计学意义（P0.05）。结论：在临床上使用利凡诺联合米非司酮与米索前列醇终止14～28周中期妊娠效果显著，能够明显减少胎盘胎膜残留，减少阴道出血量，并发症的发生率也降低，患者妊娠物排出时间也大大缩短，减少了患者的痛苦，值得临床推广使用。 　　关键词 米索前列醇 米非司酮 利凡诺 终止妊娠 　　Clinical analysis of mifepristone and misoprostol combined with intra amniotic injection of rivanol in termination of midtrimester pregnancy 　　Pang Lin 　　Department of Obstetrics and Gynecology，the Maternal and Child Hospital of Qianjiang District，Chongqing City 409000 　　Abstract Objective：To investigate the clinical effect of mifepristone and misoprostol combined with intra amniotic injection of rivanol in ending of midtrimester pregnancy，and to explore the incidence of complications，in order to provide more theoretical basis for ending of midtrimester pregnancy.Methods：300 pregnant women of 14～28 weeks were selected from January 2008 to January 2013.Retrospectively analyze their clinical datas.Results：In the observation group，the total effective rate of terminal pregnancy was 97.33%，and that in the control group was 80.67%.The difference was statistically significant between the two groups（P0.05）.The difference in pregnancy elimination time and postoperative complications and so on was statistically significant between the control group and the observation group（P0.05）.Conclusion：The use of rivanol combined with mifepristone and misoprostol in ending of midtrimester pregnancy had significant clinical effect.It can obviously reduce the retained placenta and the amount of vaginal bleeding，and also can reduce the incidence of complications，shorten the pregnancy elimination time greatly，and reduce the pain of patients，so it is worthy of promoting in clinical. 　　Key words Misoprostol；Mifepristone；Rivanol；Terminal pregnancy