比较风险评估不完整完整( comparative risk assessmentfor intactand non- intact).docVIP

比较风险评估不完整完整( comparative risk assessmentfor intactand non- intact).doc

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INTERPRETIVE SUMMARY COMPARATIVE RISK ASSESSMENT FOR INTACT (NON-TENDERIZED) AND NON-INTACT (TENDERIZED) BEEF March 18, 2002 RISK MANAGEMENT REQUESTS AND OBJECTIVES In October 2001, the Office of Policy, Program Evaluation and Development (OPPDE) requested the following types of risk assessments to support policy decision-making regarding E. coli O157:H7 in non-intact beef: a farm-to-table risk assessment to evaluate the effectiveness of interventions in reducing the occurrence and extent of E. coli O157:H7 contamination on carcasses and reduce the subsequent risk of illness; and a comparative risk assessment to evaluate the risk of illness per serving from intact versus non-intact (e.g., tenderized) beef steaks and roasts prepared using traditional cooking practices (grilling, broiling, and frying). The requested farm-to-table risk assessment for non-intact (tenderized) beef could not be developed because of the lack of sufficient data on the prevalence and level of E. coli O157:H7 on specific locations of the carcass (see the Risk Assessment Plan for Non-Intact Beef; FSIS 2001). There was, however, sufficient data to assess the risk of illness from non-intact (tenderized) beef compared to intact (non-tenderized) beef. The comparative risk assessment, including modeling approach, data inputs and underlying assumptions, as well as the resulting risk estimates are summarized below. For additional technical detail, see the Technical Report: Comparative Risk Assessment for Intact (Non-Tenderized) and Non-Intact (Tenderized) Beef (FSIS, March 2002). PUBLIC HEALTH REGULATORY CONTEXT Public Health Background E. coli O157:H7 was first recognized as a foodborne pathogen with major public health consequences in 1982, when it was associated with two outbreaks of bloody diarrhea in Oregon and Michigan. An estimated 62,000 cases of symptomatic E. coli O157:H7 infections occur annually in the United States due to foodborne exposures, resulting in approximately 1,800 hospit

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