实验室生物安全分解.ppt

OHS 4 Laboratory Biosafety实验室生物安全 Objectives目的 By the end of this session you will have an understanding of须了解: Classifications of biohazardous material危险生物材料分类 Risk group pathogens病原体危险性分组– definitions定义 Routes of exposure接触途径 Barriers for containment隔离设施 Methods of decontamination排除污染的方法 Definition定义 Biohazardous Materials 危险生物材料: Biological agents or substances present in, or arising from, the work environment which presents, or may present, a hazard to the health or well being of the worker or community存在、或产生于工作环境，可能导致群体或个人的健康危害的生物介质或物质 Biohazardous Agents危险生物介质 Classified into eight groups分为8组: cultured animal cells and the potentially infectious agents these cells may contain培养的动物细胞，并可能发生感染 primate body fluids and other potentially infected clinical specimens灵长类动物体液和可能传染的医用样品 microorganisms including Bacteria, Viruses, Fungi, Rickettsiae and Chlamydiae微生物类包括细菌、病毒、真菌、立克次氏体和Chlamydiae等 Biohazardous Agents危险生物介质 Parasites寄生虫 Allergens过敏原、 tissues from experimental animals including animal dander实验动物组织包括动物头屑 plant viruses, bacteria and fungi植物病毒、细菌和真菌 toxins (bacterial, animal or plant)生物毒素（细菌、动物或植物） Laboratory Biosafety实验室生物安全 Two main sources of Biohazardous material in use in most Laboratories实验室常用危险生物材料的两个主要来源: Pathogens used and tested for in Micro Dept微生物实验室试验用病原体 Biological fluid samples (eg. Plasma, urine), submitted for chemical analysis用于化学分析的生物液体样品（如血浆、尿） Laboratory Biosafety实验室生物安全 The risk group of pathogens as classified by WHO世界卫生组织对病原体危险性分组 Risk Group 1 Agents 第一组介质 Low individual and community risk 低个体和群落风险 Risk Group 2 Agents第二组介质 Moderate individual risk, limited community risk中度个体风险，有限群落风险 Risk Group 3 Agents第三组介质 High individual risk, low community risk高个体风险，低群落风险 Risk Group 4 Agents第四组介质 High individual risk, high community risk高个体风险，高群落风险 Risk Group 1 Agents第一组介质 Non-pathogenic bacteria, fungi非病原体细菌、真菌 No special facilities, equipment or procedures are required无需特殊设备或操作 Standard well-designed experimental animal and labora