分子生物学概述剖析.ppt

Figure 1. The Basis of the ceRNA Language How mRNAs affect microRNAs is less well characterized than how microRNAs affect mRNAs. (A) The relationship between mRNAs and microRNAs could be reciprocal (Seitz, 2009), causing the level of one mRNA to influence the level and activity of another mRNA. (B) Thus, RNA molecules could communicate with each other through microRNA and microRNA response sequences (MREs). The greater the number of shared MREs, the greater the level of ‘‘communication’’ and thus coregulation. (C) The 30 UTRs of RNA molecules contain MREs, which can function in cis to regulate