ppt课件-significanceanalysisofmicroarrays(sam).pptVIP

Significance analysis of microarrays (SAM) SAM can be used to pick out significant genes based on differential expression between sets of samples. Currently implemented for the following designs: - two-class unpaired two-class paired multi-class censored survival one-class SAM SAM gives estimates of the False Discovery Rate (FDR), which is the proportion of genes likely to have been wrongly identified by chance as being significant. It is a very interactive algorithm – allows users to dynamically change thresholds for significance (through the tuning parameter delta) after looking at the dis