ppt课件-weightedleastsquaresregression-universityofflorida.pptVIP

Weighted Least Squares Regression Dose-Response Study for Rosuvastin in Japanese Patients with High Cholesterol Randomized Dose-Response Study of Rosuvastin in Japanese Patients with Hypercholesterolemia Saito, et al, Journal of Atherosclerosis, 2003, 10:329-336 Weighted Least Squares (Independent Case) Errors are independent Variance of errors are not all equal (Heteroscedastic) Variances may be known or estimated Estimates can be obtained by regression when the variance is a power function of the mean General case with known variance structure (up to s2): Weighted Least Squares Procedur