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Chemistry CHAPTER 5: SIGNALS AND NOISE The signal to noise ratio: (S/N) The fundamental concepts of noise and signal-to-noise ratio are central to the discipline of analytical chemistry. Since chemical instrumentation dominates the modern laboratory, it is critical that students understand the role noise plays in limiting the precision of a measurement. It is equally important that they understand how to implement active and passive means to mitigate noise. The purpose of this Mathcad document is to allow the student to gain a familiarity with the concepts of signal-to-noise ratios and to ex