STEROIDCHEMISTRYANDUSE.pptVIP

steroids STEROID CHEMISTRY AND USE SECONDARY SEX CHARACTERISTICS CHEMICAL CONTROL ANTIINFLAMMATORY NOTE: Information written in red(underlined in handout) may be tested- information in black is not going to be on the exam Major reference material- Hill Kolb, CHEMISTRY FOR CHANGING TIMES, 9th Ed, pp566-573 Grant, Ellen Dr. “ THE BITTER PILL” 1985 “SEXUAL CHEMISTRY” 1996. Marschall, L., “The Sciences” p.1111, Nov/Dec1995. (This reference has the quote from Sanger concerning reason for “pill” development) Additional References Dr Christiane Northrup, “ Women’s Bodies, Women’s Wisdom”, Revised 1998, Bantam, NY, NY, mainly pp 392-407. (Some information on Natural Family Planning, NFP) Katherine Davis, Self, Dec 2000, p.82 (more info on NFP) Jackie Cissell JoelBrind Additional References Seaman, Barbara, “The Doctor’s Case Against the Pill”, Doubleday-Dolphin, Garden City, New York, 1980. This book is on 2 hour reserve for Chem. 100 in Milne. STEROID STRUCTURAL CHARACTERISTICS: Structure is based on the ring structure below: SMALL STRUCTURAL DIFFERENCES HAVE PROFOUND CONSEQUENCES ANDROGENS-1 Blood Clotting Testicular Atrophy Difficulty in urinating Male Pattern Balding Decreased Sperm Production Impotence Hypertension SIDE EFFECTS / MEN / ANDROGENS#3: Insulin Resistance Inability to Ejaculate High Cholesterol Fluid Retention Heart Attack Risk of Kidney Disease Increased Mental Disorders (Roid Rage) ANDROGEN SIDE EFFECTS / WOMEN Enlargement of Clitoris(1) Loss of Body Curves Deepening of Voice Menstrual Problems Irreversible Pattern Baldness ESTROGENS, PROGESTINS- BIRTH CONTROL PILLS Can control male as well as female fertility- dropped as male pill Use as male pill dropped when one man was found to have testicular atrophy* Three women died- the formula was changed and the tests proceeded!!* In women, the pill simulates pregnancy *From Dr Ellen Grant “The Bitter Pill” Pill “ According to the Western model, pregnancy is a disease, menopause is a disease, a