雌激素调控子宫内膜癌ishikawa细胞中lrp16基因表达及其意义.docVIP

雌激素调控子宫内膜癌Ishikawa细胞中LRP16基因表达及其意义 作者：孟元光，韩为东，黄柯，伍志强，赵亚力，母义明，宋磊 【关键词】 LRP16基因；雌激素；Ishikawa细胞；E 　　Expression regulation of LRP16 gene by 17βestradiol and its significance in human endometrial cancer Ishikawa cells 　　【Abstract】 AIM: To explore the regulation of LRP16 gene expression by 17βestradiol (E2) in ERαpositive human endometrial cancer Ishikawa cell line, and to investigate the effect of LRP16 overexpression on the proliferative potential and invasive growth of Ishikawa and the possible molecular mechanism. METHODS: The LRP16 mRNA level in