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Risks and Benefits listed in examples are for example purposes only. See Form C instructions to details of how to analyze risks in a research submission. Risks and side effects related to the study drug XCDFR include: Likely (10 or more subjects out of 100) Not Serious Serious Cough Headache Nausea Tiredness (fatigue) None Less Likely (Between 2-9 subjects out of 100) Not Serious Serious Chest discomfort Chest pain Shortness of breath Chills Fever Muscle spasms Muscle pain Leg (extremity) pain Mouth or throat sores (stomatitis) Decreased levels in blood magnesium Loss of appetite