嗜麦芽窄食单胞菌医院感染分布及耐药性分布.doc

嗜麦芽窄食单胞菌医院感染分布及耐药性分析 (江西省抚州市人民医院【摘要】 目的 探讨医院感染在临床标本中的分布及耐药性，为临床医师合理用药提供科学依据。 方法 采用对临床送检标本分离的菌株进行药敏试验，分析其耐药性。 结果 株菌株主要来源于痰液占%)，其中55.56%的病人使用机械通气治疗48小时以上，科室主要分布于重症监护病房(ICU)、神经和呼吸内科等。对的敏感率为%，对左氧氟沙星头孢吡肟、头孢他啶、的敏感率在%～%之间对的敏感率仅为%。对以上抗菌药物。 结论耐药性已十分严重临床应根据药敏结果合理使用抗生素。 【关键词】 医院感染；； 分布； 耐药性Distribution and Drug-resistance of Stenotrophmomas maltophilia in Nosocomial Infections HAO Huiqing, HU limin. Department of Clinical Laboratory, The First Pepole’s Hospital Of Fuzhou City, Fuzhou, Jiangxi 344000, China ) 【Abstract】 Objective To investigate the distribution and drug-resistance of in nosocomial infections to provide the scientific evidence for the clinical use of the antibiotics. Methods To do drug sensitive test to Stenotrophmomas maltophilia isolated from clinical specimen by 96NE of the company of heima dier and to analyze the drug resistance. Results A total of 67 strains of Stenotrophmomas maltophilia were mainly isolated from sputum (about 67.16%) and mainly isolated from intensive care unit (ICU), departments of respiratory Medicine and neurosurgery, et al. And 55.56% of the patients had treated with the mechanical ventilation for 48 hours or more. The sensitive rate of Stenotrophmomas maltophilia to 14 kinds of antibiotics showed that cefoperazone/sulbactam was 79.10%. The sensitive rate of piperacillin/Tazobactam, Levofloxacin, cefepime, ceftazidime, chloramphenicol, netilmicin, ciprofloxacin, ticarcillin/clavulanic, tobramycin, co-trimoxazole, piperacillin, cefoperazone were about from 25.37% to 49.25%; The sensitive rate of cefotaxime was only 17.91%. It is showed that the Stenotrophmomas maltophilia has a high resistance rate to the 14 kinds of antibiotics. Conclusion Drug-resistance status of Stenotrophmomas maltophilia is very serious. Clinician should use antibiotics rationally according to the results of drug susceptibility test. 【Key words】Noso