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Name of journal:World Journal of GastroenterologyESPS Manuscript NO: 18963Manuscript Type:REVIEWEmerging role of Hippo pathway in gastric and other gastrointestinalcancersKang W et al. Hippo pathway deregulation in gastric carcinogenesisWei Kang, Alfred SL Cheng, Jun Yu, Ka Fai ToWei Kang, Ka Fai To, Department of Anatomical and Cellular Pathology, State Key Laboratory in Oncology in South China, Li Ka Shing Institute of Health Science, Sir Y.K. Pao Cancer Center, Institute of Digestive Disease, Partner State Key Laboratory of Digestive Disease, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, ChinaAlfred SL Cheng,School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, ChinaJun Yu,Department of Medicine and Therapeutics, Institute of Digestive Disease, Partner State Key Laboratory of Digestive Disease, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, ChinaAuthor contributions:To KF provided direction and guidance throughout the preparation of this manuscript. Kang W conducted the literature review and drafted the manuscript.Cheng ASL and Yu J reviewed the manuscript and made significant revisions on the drafts.Supported by General Research Fund (2140855, RGC Reference No. CUH from The Research Grants Council of Hong Kong, National Natural Science Grant from China, and Direct Grant for Research (No. 2014.2.002) from The Chinese University of Hong Kong.Conflict-of-interest statement: The authors report no conflicts of interest.Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-