Dietary exposure to 5hydroxymethylfurfural from Norwegian膳食暴露于5羟甲基糠醛从挪威.pptVIP

下载本文档

1
0
约2.55千字
约 14页
2017-02-10 发布于上海
举报
版权申诉

Dietary exposure to 5hydroxymethylfurfural from Norwegian膳食暴露于5羟甲基糠醛从挪威.ppt

1、本文档共14页，可阅读全部内容。
2、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。
3、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
5、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
6、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
7、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
8、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

Dietary exposure to HMF from Norwegian food and correlations with urine metabolites of short-term exposure T. Hus?y, M. Haugen, M. Murkovic, D. J?bstl, L.H. St?len, T. Bjellaas, C. R?nningborg, H. Glatt, J. Alexander Metabolism of HMF DNPH-derivatives of HMF Chromatogram of HMF-DNPH in urineRP, 400 nm Renal excretion of HMF GC analysis of HMFA in urineafter silylation with BSTFA/TMCS HMF and HMFA Chromatogram of HMF and HMFA in urine Study design 47 non-smokers + 6 smokers (2 ♂, 4 ♀) (53 participants) 24 h dietary recall 24 h collection of urine 20 ♂ (45 ? 13) + 33 ♀ (41 ? 11) Foods (35) from the 24 h dietary recall were purchased and analysed for HMF and HMFA 26 contained HMF and 10 HMF Food groups containing HMF and HMFA Norwegian brown cheese Jam and honey Cereal products Dried fruits Fruit juices Coffee Beer Coffee Cereal products HMF and HMFA in Norwegian food products Contribution of single food groups to the uptake of HMF Estimated 24 h dietary intake and 24 h urinary excretion of HMFA Correlation between 24 h dietary intake of HMF, HMFA, HMF + HMFA, coffee, dried fruits and beer, and 24 h urinary excretion of HMFA (n = 53) rsp = Spearman’s rank correlation coefficient. * Graz University of Technology Institute of Biochemistry Functional Food Group EUROPEAN COMMISSION FOOD QUALITY AND SAFETY Food and Chemical Toxicology 46 (2008) 3697–3702 O O H O O O O S O O O O O H O O H Sulfotransferases proposed pathway Oxidation main pathway in kidneys and urinary excretion 1 nd 5.8 Canned peaches 1 nd 237 Prunes 1 nd 13.3 Dark beer 2 nd 0.2–0.3 Beer 7 40.3–130 262–547 Ground coffee 3 0.23–17.2 1.72–143 Cappuccino with added sugar, instant powder 5 5.6–174 91.3–3060 Coffee, instant 1 nd 0.30 100% apple juice 1 nd 5.00 Raisins 1 nd 0.61 Wholemeal rusk 1 0.70 0.65 Crispbread, wafer-thin 1 nd 0.45 Crispbread, thin, made of rye 2 nd – 0.07 0.06 – 0.14 Bread 1 0.02 0.24 White bread 1 nd 0.37 Cereals with dried fruits 1 0.05 0.34 Honey 1 nd 0.20 Soft brown cheese,