2型糖尿病合并高血压52例临床分析.docVIP

2型糖尿病合并高血压52例临床分析 　　doi：10.3969/j.issn.1007-614x.2014.21.11 　　摘 要 目的：探讨总结2型糖尿病合并高血压降压效果。方法：2013年1-12月收治2型糖尿病合并高血压患者52例。随机分成两组，治疗组30例，对照组22例。对照组给予常规治疗，并加服厄贝沙坦。而治疗组在常规治疗的基础上加服硝苯地平进行治疗。观察患者的反应，并记录相关的数据。结果：52例患者经治疗后的血糖均有明显的下降。治疗组降压的总有效率96.67%，比对照组的总有效率81.81%要高，治疗前后差异有统计学意义（P0.05）。结论：联合用药的方式可以实现对血糖和血压的有效控制，且不良反应也减少，值得广泛应用与推广。 　　关键词 高血压 2型糖尿病 治疗效果 厄贝沙坦 硝苯地平 联合用药 　　Clinical analysis of 52 cases of type 2 diabetes mellitus combined with hypertension 　　Xu Li 　　Wuyang Community Health Service Center of Xinjin County，Chengdu City，Sichuan 611430 　　Abstract Objective：To explore and summarize the antihypertensive efficacy of type 2 diabetes mellitus combined with hypertension.Methods：52 type 2 diabetes mellitus patients with hypertension were selected from January to December 2013.They were randomly divided into two groups.The treatment group was 30 cases，and the control group was 22 cases.The control group were given conventional treatment，and plus oral irbesartan.While the treatment group plus oral nifedipine treatment on the basis of conventional treatment.The reaction of patient was observed.The relevant data was recorded.Results： 52 cases with blood sugar after treatment had obvious decline.The total effective rate of lowing blood pressure in the treatment group was 96.67%，which was higher than the total effective rate（81.81%） of the control group.The difference was statistically significant（P0.05） before and after the treatment.Conclusion： Drug combination method can realize the effective control of blood glucose and blood pressure，and has decreased adverse reactions.It is worthy of wide application and popularization. 　　Key words Hypertension；Type 2 diabetes mellitus；Treatment effect；Irbesartan；Nifedipine；Drug combination 　　糖尿病是由于体内胰岛素缺乏或胰岛素在靶细胞不能发挥正常生理作用而引起的糖、蛋白及脂肪代谢紊乱的一种综合征[1]。而2型糖尿病是糖尿病中严重的一种。2型糖尿病的病因是由于胰岛β细胞分泌胰岛素不足或靶细胞对胰岛素不敏感（胰岛素抵抗）所致，又被称作是非胰岛素依赖性糖尿病。而且在糖尿病患者中，2型糖尿病所占的比例约95.00%。临床观察胰岛素抵抗普遍存在于2型糖尿病中，高达90.00%左右。糖尿病是一种终身疾病，虽然不能彻底治愈，但能控制。其中饮食疗法是治疗糖尿病的基础，运动疗法是2