吸烟与心血管疾病.pptVIP

* Key Point Quitting smoking reduces the risk of cardiovascular events. Background Quitting smoking substantially reduces the risk of all-cause mortality in individuals with CHD. A 2003 review of 9 electronic databases containing data from 1966 to 2003 for prospective cohort studies of patients with CHD, found that those who quit smoking had a 36% reduction in odds of all-cause mortality.1 A reduction in risk of cardiac events is evident even among those who recently quit. In a German study of 967 patients aged 30–70 years who already had experienced an acute coronary event, Twardella et al found that the odds ratio (OR) for subsequent cardiovascular events decreased according to smoking status. Based on serum cotinine levels, patients were classified as never smokers, former smokers, and current smokers. Patients who said they smoked but who were negative for cotinine were classified as recent quitters. Assigning an OR of 1.00 for current smokers, the OR for recent quitters was 0.71, 0.64 for former smokers, and 0.44 for those who never smoked.2 References 1. Critchley JA, Capewell S. Mortality risk reduction associated with smoking cessation in patients with coronary heart disease: a systematic review. JAMA. 2003;290:86–97. 2. Twardella D, Kupper-Nybelen J, Rothenbacher D, Hahmann H, Wusten B, Brenner H. Short-term benefit of smoking cessation in patients with coronary heart disease: estimates based on self-reported smoking data and serum cotinine measurements. Eur Heart J. 2004;25:2101–2108. 1/Critchley/p 86/abstract 2/Twardella/ p. 2106/ Table 4; p 2107/col 2/?2 2/Twardella/p. 2101/ abstract; p. 2102/col 1/?5; p. 2106/ Table 4 1/Critchley/p 86/ abstract/p87 methods * 同时，戒烟还能提高冠脉介入治疗后患者的生存率，本图为我们展示了经冠脉介入治疗后的戒烟者比相同情况的吸烟者生存率下降明显延缓，说明戒烟能延缓冠脉介入治疗后的死亡。 Key Point Persistent smokers had a significantly greater risk of overall mortality after percutaneous coronary revascularization. Patients (N=6600) who underwent percutaneous coronary revascularizatio