思他宁联合手术治疗结肠癌合并肠梗阻的效果及临床意义.docVIP

思他宁联合手术治疗结肠癌合并肠梗阻的效果及临床意义 　　[摘要] 目的 分析思他宁联合手术治疗结肠癌合并肠梗阻的效果和临床意义，以供参考。 方法 选择2011年3月～2013年2月西安医学院第二附属医院收治的结肠癌合并肠梗阻患者93例为研究对象，所有患者均接受手术治疗。根据就诊顺序奇偶数法分为对照组（n=47）和实验组（n=46），对照组患者接受常规治疗，实验组患者在对照组治疗的基础上给予思他宁治疗。比较两组术后并发症发生情况及体液免疫水平。 结果 实验组患者术后并发症发生率（4.34%）明显低于对照组（17.02%）；实验组IgM、IgA、IgG水平[（1.15±0.33）、（2.28±0.45）、（8.06±1.28）g/L]均高于对照组[（0.83±0.25）、（1.56±0.31）、（7.35±1.24）g/L]，差异均有统计学意义（P 0.05）。 结论 思他宁联合手术治疗结肠癌合并肠梗阻可明显改善患者机体免疫功能，减少术后并发症，有利于患者的康复。 　　[关键词] 思他宁；结肠癌；肠梗阻；效果；临床意义 　　[中图分类号] R574.2 [文献标识码] A [文章编号] 1673-7210（2014）08（a）-0030-04 　　Effects and clinical significance of Stilamin combined with operation in treatment of patients with colon cancer and intestinal obstruction 　　ZHANG Huazhou1 DING Siqin1 WANG Duo1 WEI Hongcheng2 　　1.The Second Affiliated Hospital of Xian Medical College， Shaanxi Province， Xian 710038， China； 2. Department of Gastroenterology， the First Hospital Affiliated to Jinan University， Guangdong Province， Guangzhou 510630， China 　　[Abstract] Objective To analyze the effects and clinical significance of Stilamin and operation in the treatment of colon cancer and intestinal obstruction， and offer the reference. Methods 93 patients with colon cancer and intestinal obstruction from March 2011 to February 2013 in the Second Affiliated Hospital of Xian Medical College were selected as study objects， and all patients were treated with operation， they were divided into control group （n=47） and experimental group （n=46） according to visiting sequence of odd and even number method， patients in the control group were received the routine treatment， patients in the experimental group were treated with Stilamin on the basis of the reatment of the control group. The postoperative complications and humoral immunity of the two groups were compared. Results The rate of complication in the control group （17.02%） was lower than that of the experimental group （4.34%）； the levels of IgM， IgA， IgG in the experimental group [（1.15±0.33）， （2.28±0.45）， （8.06±1.28） g/L]