Serum free light chain assays an Overview血清游离轻链分析概要.pptVIP

A diagnostic process toward AL amyloidosis and light chain deposition disease (AAL/LCDD) is activated every time in patients with nephropathy a monoclonal protein is documented sFLC search was usually made in patients with: proteinuria w/wo nephrotic syndrome and renal failure or in presence of AAL suggestive symptoms * * * Chemotherapy may not stop FLC production for months - longer than PE procedures and longer than renal recovery times from cast nephropathy. Clark 97 No biopsies Creatinine 200 ?mol/L 29 dialysis dependent 5 – 7 No sFLC MP or VAD Composite of death, dialysis dependenc