四妙散加味联合左卡尼汀治疗少、弱精症疗效观察.docVIP

四妙散加味联合左卡尼汀治疗少、弱精症疗效观察 　　【摘要】目的：观察中药四妙散加味治疗湿热下注证少、弱精症临床疗效。方法：选取符合标准的42例患者，服用四妙散加味和左卡尼汀口服液联合治疗。结果：42例患者治疗后痊愈16例，显效18例，有效4例，无效4例，总有效率为90.48%。治疗4周后自身前后对照精液量、活动率、精子密度、（a+b）级精子含量差异均无统计学意义（P0.05）；治疗8周后差异具有统计学意义（P0.05）；治疗12周后差异具有显著统计学意义（P0.01）。结论：四妙散加味联合左卡尼汀口服液治疗少、弱精症具有较好临床疗效，值得进一步研究。 　　【关键词】四妙散；湿热下注证；少、弱精症 　　【Abstract】Objectives： To observe the clinical curative effect of traditional Chinese medicine （TCM） Simiaosan jiawei in treating asthenozoospermia. Methods： 42 patients meeting the criterion were selected and treated with Simiaosan jiawei combined with l-carnitine. Results： According to the results of 42 patients， there were 16 cured cases after treatment， 18 cases with markedly effect， 4 cases with effective results and 4 invalid cases. The total effective rate was 90.48%. The differences in semen quantity， activity rate， sperm density， and sperm （grade a + b） content between 4 weeks after treatment and before the treatment had no statistical significance （P 0.05）. The difference between 8 weeks after treatment and before the treatment was statistically significant （P 0.05）； The differences between 12 weeks after treatment and before the treatment had statistical significance （P 0.01）. Conclusion： Simiaosan jiawei combined with l-carnitine has good clinical curative effect in the treatment of asthenozoospermia， which is worthy of further investigation. 　　【Key words】Simiaosan jiawei； Damp-heat syndrome； Asthenozoospermia 　　【中图分类号】R277.33【文献标志码】A 　　据统计我国育龄夫妇中不孕不育患者约占10%，其中男方因素占30%3.41 years old， and the pelvic organ prolapse quantification （POP-Q） stage was III～IV stage. Pre- and post-operative symptoms were assessed using the urinary distress inventory （UDI-6） and the incontinence impact questionnaire （IIQ-7）， and the international continence society criteria were used for the urodynamic evaluation. Results： Among the total 30 patients， 22 patients underwent partial colpocleisis and another 8 underwent the total colpocleisis. Seven women underwent also a con