高敏C反应蛋白水平变化与停用主动脉内球囊反搏术时机关系的研究.docVIP

高敏C反应蛋白水平变化与停用主动脉内球囊反搏术时机关系的研究 　　【摘要】 目的：探讨高敏C反应蛋白（hs-CRP）水平变化与停用主动脉内球囊反搏术（IABP）时机关系。方法：选取本院2013年1月-2015年5月诊治的急性心肌梗死并行IABP辅助治疗的患者43例，根据IABP球囊导管撤除后患者血hs-CRP变化趋势，将患者分为hs-CRP上升趋势组20例及hs-CRP下升趋势组23例，比较两组患者病情好转情况、病死率及住院时间。结果：与hs-CRP上升组比较，下降段组病情好转率高（86.9% vs 50.0%），病死率低（4.3% vs 30.0%），住院时间缩短（13.6±6.2）d 　　vs （18.4±6.8）d，两组比较差异均有统计学意义（P0.05）。结论：IABP辅助治疗急性心肌梗死，在血hs-CRP处于下降阶段时撤除球囊导管临床治疗效果改善更佳。 　　【关键词】 高敏C反应蛋白； 主动脉内球囊反搏术； 急性心肌梗死 　　Research on Relationship between Changing Trend of Hs-CRP and Occasion of Withdrawing IABP Balloon Catheter in Patients with Acute Myocardial Infarction/LIN Xi-min，HUANG Nan-he，ZHOU Cong，et al.//Medical Innovation of China，2016，13（22）：112-115 　　【Abstract】 Objective：To investigate the relationship between changing trend of hs-CRP and occasion of withdrawing IABP balloon catheter in patients with acute myocardial infarction.Method：A retrospective review was performed on 43 patients with acute myocardial infarction（AMI） who had used IABP in our department from January 2013 to May 2015. The patients according to the change trend of serum hs-CRP in the occasion of withdrawing balloon catheter were divided into hs-CRP increasing group of 20 cases and hs-CRP decreasing group of 23 cases.The improvement rate，mortality rate and hospital stay time of two groups were compared.Result：In hs-CRP decreasing group，compared with hs-CRP increasing group，the improvement rate was higher （86.9% vs 50.0%，），mortality rate was lower（4.3% vs 30.0%） and hospital stay time was shorter（13.6±6.2）d vs （18.4±6.8）d，the difference was statistically significant（P0.05）.Conclusion：In the assistant treatment of AMI with IABP，the balloon catheter is withdrawing during the period of serum hs-CRP decreasing and curative effect will be better. 　　【Key words】 High-sensitivity C-reactive protein； Intra-aortic balloon pumping； Acute myocardial infarction 　　First-author’s address：Zhongshan City Xiaolan People’s Hospital，Zhongshan 528415，China 　　doi：10.3969/j.issn.1674-4985.2016.22.03