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CHAPTER 9. QUANTITATIVE GENETICS
1. Quantitive variation in a trait can be caused by as few as _______ simple Mendelian loci that each have _______ alleles.
a. 16; 4
b. 6; 2
c. 10; 3
Correct answer: B
2. Edward East investigated whether or not Mendelian genetic models could be applied to the study of quantitative traits by studying corolla length in long flower tobacco. He began with two pure-breeding strains, one with long corollas and one with short corollas. One of his central predictions was that, if the Mendelian model applied, the range of variation in his F2 hybrids would not extend all the way to the original parental phenotypes. Which of the following best explains why?
Correct answer: He confirmed this by successfully breeding for long- and short-corolla plants in later generations. Had the alleles been lost, he could not have recovered the parental phenotypes. See pp. 2-5.
3. Regarding Edward Easts study: What were Easts two predictions regarding whether independent Mendelian loci can produce quantitative variation? Did his results match his predictions?
Correct answer: ? East predicted that if quantitative variation in a trait is due to Mendelian loci, then (1) the range of variation in the F1 generation will not extend all the way to the parental phenotypes, and (2) it should be possible to re-create the original parental phenotypes in just a few generations of selective breeding. The results matched his predictions.
4. Quantitative trait locus (QTL) mapping can tell us which of the following?
a. all of these,
b. the location of QTL in the genome
c. both the number of loci that influence a quantitative trait and the location of QTL in the genome.
d. the identity of QTL and the proteins they encode .
Correct Answer: both the number of loci that influence a quantitative trait and the location of QTL in the genome ? QTL mapping can also tell us the magnitude of t
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