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Objective and subjective assessing efficacy of a lubricating drop in eyes wearing silicone hydrogel contact lenses.pdf

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Objective and subjective assessing efficacy of a lubricating drop in eyes wearing silicone hydrogel contact lenses.pdf

HOSTED BY Available online at ScienceDirect Journal of Current Ophthalmology 28 (2016) 69e74 /journal-of-current-ophthalmology Original research Objective and subjective assessing ef?cacy of a lubricating drop in eyes wearing silicone hydrogel contact lenses Amir Asharlous a,*, Ali Mirzajani b, Ebrahim Jafarzadehpur b, Mehdi KhabazKhoob c, Hadi Ostadimoghaddam d a Optometry Department, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran b Optometry Department, Iran University of Medical Sciences, Tehran, Iran c Department of Medical Surgical Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran d Refractive Errors Research Center, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran Received 11 December 2015; revised 30 March 2016; accepted 31 March 2016 Available online 24 May 2016 Abstract Purpose: To investigate the effect of a lubricating drop on optical quality, tear ?lm stability, and subjective symptoms in individuals wearing silicone hydrogel contact lens. Methods: In this one-day, prospective single-center clinical study, Pre-lens Tear Deformation Time (PL-TDT), Root-Mean-Square (RMS) of Low Order Aberrations (LOA) and High Order Aberrations (HOA), individual twelve Zernike coef?cients, and subjective symptoms were assessed in 43 volunteers (mean age 19.58 ± 1.63, 86 eyes) at 6 h after inserting the contact lens and then at 60 min after instilling a lubricating drop (Comfort drops, Avizor, Madrid-Spain). Results: PL-TDT, LOA-RMS, and HOA-RMS values measured before drop instillation were not signi?cantly different with those measured after drop. None of the Zernike coef?cients were signi?cantly different after instilling lubricating drop. Statistically signi?cant decrement in both frequency and severity values in blurry vision, dryness, discomfort, burning, itching, foreign body sensation, excessive blinking, and lacrimation were seen after dr