肝硬化的临床流行病学分析.PDF

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肝硬化的临床流行病学分析.PDF

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38 Chin J Clini Hepatol ,February 2001 ,Vol117 ,No11 (11 150001 ; 31 1, 1, 1, 2, 3, 3, 1 , 150086 ; 21 , 150036) , HBV () HBV , HBs x x2 P 1139 % , HBV , ; R57512 51107 % 11179 % HBsAg + HBe + HBc HBsAg + HBc , (80142 %) , 88 % HBc HBe ; B 1001 - 5256 (2001) 01 - 0038 - 03 Clinico2Epidemiological Analysis on Liver Cirrhosis YA O Zhen , YA O Zong2ge , W A N G Y un , et al1 The Second Cli nicomedical College of Harbi n Medical U niversity , Harbi n 150086 , Chi na Abstract : Observe t he main clinico2epidemiological index of a large group of samples (8 ,016 in2patient cases) of liver cir2 rhosis1Adopting t he statistical met hod of x ,x2 and Pvalue1t he proportion of clinical onset of liver cirrhosis is 1139 % ,and accounting for 51107 % of all t he in2patients suffering from liver diseases and t he case fatality rate is 11179 %1Etiological analysis confirmed t hat 88100 % cases are correlative wit h HBV infection1 The main HBV marker pattern are HBsAg + anti2HBe + anti2HBc (40179 %) and HBsAg + anti2HBc (28171 %) ,but single anti2HBc and double anti2HBe and/ or an2 ti2HBs are not less as imagined1For direct deat h causes ,hemorrhage of digestive tract (80142 %) is t he most common cause and t he second is hepatic failure complicated wit h hepatoencephalopat hy1Most cirrhoses is correlative wit h HBV1 The aim of t he study is to evaluate t he effects for 88 % of all t he sampled liver cirrhoses cases1 Therefore to decrease t he deat h rate of cir2rhoses1pveveutian and care for hepatitis B are important1 Key words : Liver cirrhosis ; Hepatitis B virus related ; Clinico2epidemiological analysis 1 111 11111 , 11112 , 1000 , 11113 1991 1997 112 : 1997 : :2000 - 01 - 05 :3 1988 1997 286 ( x) , ( x2) :2000 - 04 - 10 ( P) 2 211 ,10 1139 % (8016/ 578540 ) , 1120 % 1155 % , (15695 ) 51107 %( 43171 % 60197 %) 212 10 11179 % ( 945/ 8016 ) , 10113 % 13155 % 213 1 , , HBV HCV 9 % 90 % HBV 2 HBV , 38 2HCV , 68 2HCV , 7116 % 38 2HCV HB2 sAg 2HBc ( 2 ) HBsAg 2HBe ( 1 ) HBsAg 2HBe 2HB