生物化学总概课件.pptVIP

生物化学（1）杨缜Office: 实验楼S-329Tel.: 2653 4152e-mail: zyang@szu.edu.cn;About this course;What is Biochemistry?;4;Why is Biochemistry so important?;What are the major differences in appearance between the leaves from the top and bottom of a tree crown and why? Why do we rarely see black flowers? Why cant most fresh water fish live in salt water and most salt water fish not in fresh water? What’s the difference in the blood color between vertebrates and mollusks? Why? Why does the blood taken for blood test look dark red but not bright red? Is collagen nutritious? Why? Do you think the fruits in fruit jelly are cooked or not? Why? What’s the proper way of using enzyme-containing washing powders? Why does fresh meat look dark in color after being displayed at a grocery store for some time? Can you add brown sugar into milk? Why? Why are some people easier to get drunk? Why can’t some people drink milk? ;Do you think the fruits in fruit jelly are cooked or not? Why?;What’s the difference in the blood color between vertebrates and mollusks? Why?;Biochemistry;10;Arrangements Requirements;Contents;Chapter 1. General Introduction;I. Living organisms vs. inanimate objects;II. Biomolecules;Component;Normal Chemical Composition for a Man Weighing 65 kg;1. Major types of biomolecules;Elementary composition of the human body (dry weight basis);2. Biomolecular hierarchy;Structural hierarchy in the molecular organization of cells;A classic experiment on the abiotic origin of organic biomolecules by Miller and Urey (1953);3. Chemical principles governing properties of biomolecules;2). Structure Composition(组成) Constitution(构造) Configuration(构型) - changed by bond breakage Conformation(构象) - changed by bond rotation ;马来酸;3). Stereoisomers(异构体) Stereoisomers are compounds that have Same constitutions (相同构造) Different configurations (不同构型) Stereoisomers are caused by the presence of Double bonds: cis-trans isomers (顺反异构) Chiral centers: n chiral carbons ? 2n max stereo