公办药学专业《有机化学1》期末试卷13.docVIP

温州医学院 考试科目：Organic Chemistry I.Choose a letter that designates the correct order of the assigned properties:（16%） 1. Which compound is most stable for the following compounds: ( ) 2. For the following compounds which has no characteristic IR absorption at 3300and 3000 cm -1？( ) 3． For the following compounds which one is most reactivity in electrophilic reaction of aromatic ring? ( ) 4．For the following compounds which one is difficult in the both reaction of SN1，SN2( ) 5．For the following compounds which could not undergo iodoform reaction?( ) A Ethanol B acetone C Propanal D butanone 6．The order of Acidity of (1) (2) (3) (4) is: ( )？ 1．Ethyne 2. Ethanol 3. Acetic acid 4. Phenol A 3 4 2 1 B 3 2 4 1 C 4 3 2 1 D3 4 1 2 7. For the following compounds which is weakest base？( ) A Pyridine B Quinoline C amine D Pyrrole 第一 页，共 5 页 8．Which Grignard reagents could be prepared directly by using the following reaction of halide with Mg ? ( ) A. HOCH2CH2Br, B. C. D. II、Predict the major product in each of the following reactions: (32%) 1． ？ 2． 3． 4． 5． 6． ？ 7． 8． 9．第二 页，共 5 页 10． 11． 12． 13． 14． 15． 16． III. How would you prepare the following compounds, starting with corresponding starting materials and any other reagents needed. The procedure may contain several steps. (24%) 1． 2． 3． 4．  第三 页，共 5 页 5． 6． IV. Mechanism（12%） 1． 2． V. Propose the structure for the following compounds that fit the corresponding conditions(10%） Propose the structure for C5H10O that fit the following 1 NMR data The spectra has only two single peak. δH：1.02（d，6H），2.12（s，3H），2.22（m，1H） δH：1.05（t，6H），2.47（q，4H） 2. Compounds A: C6H14，when A reaction with chlorine, 3 ( B，C and D) of different monochlorides could be provided. B and Ｃ could react with Pot