环境微生物学的组学技术应用和突破_省略__环境微生物学的组学技术_英文_杨云锋.pdfVIP

微生物学通报 Jan. 20, 2013, 40(1): 18?33 Microbiology China ? 2013 by Institute of Microbiology, CAS tongbao@ 专论与综述 在气候变化、环境污染生物清除、农田肥力保持等重要领域, 以宏基因组学为基础的系列组学 技术的应用已极大地加深了人们对科学规律的认识。 杨云锋 Omics breakthroughs for environmental microbiology Running title: Omics for environmental microbiology YANG Yun-Feng* (State Key Joint Laboratory of Environment Simulation and Pollution Control, School of Environment, Tsinghua University, Beijing 100084, China) Abstract: To discover and characterize microbial members within their community and their roles in the environment, high-throughput omics approaches are being developed and applied. Among them, sequencing- and microarray-based metagenomics is the most mature key approach, providing information basis for most other omics technologies. Metatranscriptomics, metaproteomics and community metabolomics have had limited successes but already shown promising potentials. All of the omics approaches lie on the support of bioinformatics, which becomes a major bottleneck in omics applications. These new omics technologies are revolutionizing the field of environmental microbiology in revealing the genetic potentials and functional activities of microbial communities. Keywords: Microbial community, Omics, Metagenomics, Climate change, Carbon cycling, Nitrogen cycling Foundation item: National Science Foundation of China (No.; State Key Joint Laboratory of Environment Simula- tion and Poll