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Lipase member H is a novel secreted protein selectively upregulated in human lung adenocarcinomas....pdf

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Lipase member H is a novel secreted protein selectively upregulated in human lung adenocarcinomas...

Biochemical and Biophysical Research Communications 443 (2014) 1141–1147Contents lists available at ScienceDirect Biochemical and Biophysical Research Communications journal homepage: www.elsevier .com/locate /ybbrcLipase member H is a novel secreted protein selectively upregulated in human lung adenocarcinomas and bronchioloalveolar carcinomas0006-291X/$ - see front matter 2013 Elsevier Inc. All rights reserved. /10.1016/j.bbrc.2013.12.106 ? Corresponding authors at: Research Center for Stem Cell Engineering, National Institute of Advanced Industrial Science and Technology (AIST), Higashi, 1-1-1, Tsukuba 305-8562, Japan. Fax: +81 29 861 2987. E-mail addresses: asashi@bio.c.u-tokyo.ac.jp (M. Asashima), akikuri@hotmail. com (A. Kurisaki).Yasuhiro Seki a,b, Yukihiro Yoshida c,d, Hisako Ishimine b,e, Aya Shinozaki-Ushiku f, Yoshimasa Ito b, Kenya Sumitomo g, Jun Nakajima d, Masashi Fukayama f, Tatsuo Michiue a, Makoto Asashima a,b,h,?, Akira Kurisaki b,e,? aGraduate School of Arts and Sciences, The University of Tokyo, Tokyo, Japan bResearch Center for Stem Cell Engineering, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan cDepartment of Surgery, Asahi General Hospital, Chiba, Japan dDepartment of Thoracic Surgery, The University of Tokyo, Graduate School of Medicine, Tokyo, Japan eGraduate School of Life and Environmental Sciences, The University of Tsukuba, Tsukuba, Ibaraki, Japan fDepartment of Pathology, Graduate School of Medicine, The University of Tokyo, Hongo, Tokyo, Japan gDepartment of Internal Medicine, JA Kochi Hospital, Kochi, Japan h Life Science Center of Tsukuba Advanced Research Alliance (TARA), The University of Tsukuba, Tsukuba, Ibaraki, Japan a r t i c l e i n f o a b s t r a c tArticle history: Received 9 December 2013 Available online 28 December 2013 Keywords: Lipase member H Lung adenocarcinoma Bronchioloalveolar carcinoma Cell proliferation Biomarker Prognostic markerLung cancer is one of the most freque